Product Name: 5-Amino-1MQ Pen
Formulation: 2.6 mL pre-filled pen
Clicks per Pen: 240
Total Amount: 100 mg 5-Amino-1MQ
Supplied with: 6 sterile needles (extras available)
Description
5-Amino-1MQ is a synthetic small-molecule compound with the chemical name 5-amino-1-methylquinolinium (also known as 5-amino-1-methylquinolin-1-ium). It is a positively charged heterocyclic molecule structurally related to quinolinium derivatives. Mechanism of Action
5-Amino-1MQ acts as a potent and selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in adipose tissue, liver, and certain metabolically active cells. NNMT catalyses the transfer of a methyl group from S–adenosylmethionine (SAM) to nicotinamide, producing 1–methylnicotinamide and S–adenosylhomocysteine (SAH). By inhibiting NNMT, 5-Amino-1MQ:
- Reduces 1-methylnicotinamide production
- Preserves intracellular nicotinamide levels
- Increases NAD+ availability
- Shifts cellular metabolism toward oxidative pathways
- Enhances mitochondrial function and energy expenditure
- Decreases fat storage and adipocyte differentiation
These effects support improved metabolic efficiency, reduced adipose tissue accumulation, and preservation of lean mass.
Indications & Usage
5–Amino-1MQ is used to support metabolic health and body composition. It is indicated for:
- Promotion of fat metabolism and oxidation
- Preservation of lean muscle mass during weight management
- Support for energy expenditure and metabolic efficiency
- Assistance in cellular energy homeostasis and anti-aging metabolic pathways
Contraindications & Warnings
Do not use if you have:
- Known hypersensitivity to 5-Amino-1MQ or any excipient
- Severe uncontrolled hypertension or cardiac arrhythmias
- Active malignancy or history of hormone-dependent cancer
- Severe hepatic or renal impairment
- Age under 18 years
- Pregnancy or breastfeeding
Warnings
- Use only under medical supervision.
- Monitor blood pressure, heart rate, and metabolic parameters during use.
- Not a substitute for diet, exercise, or approved medical therapies for obesity or metabolic disorders. Discontinue immediately and seek medical attention if severe symptoms occur (e.g., rapid heartbeat, chest pain, severe headache, or signs of allergic reaction).
Dosage & Administration
- Subcutaneous injection only.
- Standard Dose: 5 mg (12 clicks) once daily
- (1 click≈ 0.417 mg/417 mcg)
- Alternative / Higher Dose (if tolerated): Up to 10 mg (24 clicks) daily
- Frequency: Once daily
- Timing: Morning, on an empty stomach (wait 30-60 minutes before eating) to optimize metabolic effects Cycle: 20 consecutive days on, followed by 2 weeks off (repeat as needed)
Administration Instructions
- Wash hands and prepare a clean surface.
- Attach a sterile needle.
- Dial the required number of clicks (e.g., 12 clicks = 5 mg).
- Clean injection site (abdomen or thigh) with alcohol swab.
- Insert needle at 45-90° angle and inject slowly.
- Withdraw needle, dispose safely, and cap the pen.
- Rotate injection sites to minimize irritation.
- Always inspect solution before use: Do not inject if cloudy, discoloured, or containing particles.
Side Effects
5–Amino-1MQ is generally well tolerated. Reported reactions are uncommon and usually mild/transient, including:
- Mild injection-site irritation, redness, or itching
- Transient headache or light-headedness
- Temporary changes in energy levels or appetite
- Rare mild gastrointestinal discomfort
- If any severe or persistent symptoms occur (e.g., rapid heartbeat, severe headache, or signs of allergic reaction), discontinue use and contact your healthcare provider immediately.
Storage & Handling
- Store either in refrigerator (fridge); never freeze or in a cool dry place (≤25-30°C / 77-86°F). Keep pen capped and protected from light and heat.
- After first use: Same storage conditions.
- Keep out of reach of children.
- Discard if expired or solution appears abnormal.
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IMPORTANT NOTICE
This product is not intended to diagnose, treat, cure, or prevent any disease. Statements have not been evaluated by the FDA, SAHPRA, or other authorities. Always consult a licensed healthcare provider before use, especially if pregnant, breastfeeding, under 18, or managing medical conditions.
